Correcting a B12 deficiency is like getting your life back

[Freepressright]

The title says it all. I've been battling intermittent, but still consistent brain fog and tiredness the last few years. It wasn't until a blood test showed I was B12 deficient that I did something about it, and I'm not joking, it's like getting my life back. I take acid reducers every day for my GERD (something I hate, but I can't seem to get rid of any other way) and they prevent your absorption of cyanocobalamin, the most common B12 you find in foods and vitamins.

After a shot and several weeks on a high dose B complex with methylcobalamin (the neuro-active methyl B that your body can readily use), the difference is staggering. It happened gradually, but it happened. I have not had this much stamina in years.

Yesterday I worked a full day, trained for almost two hours, cleaned my house, ran with my dog and kids and had some fun adult playtime with my girlfriend and I still had a little left in the tank.

Anyone else ever in this boat?

[Sperwer]

The title says it all. I've been battling intermittent, but still consistent brain fog and tiredness the last few years. It wasn't until a blood test showed I was B12 deficient that I did something about it, and I'm not joking, it's like getting my life back. I take acid reducers every day for my GERD (something I hate, but I can't seem to get rid of any other way) and they prevent your absorption of cyanocobalamin, the most common B12 you find in foods and vitamins.

After a shot and several weeks on a high dose B complex with methylcobalamin (the neuro-active methyl B that your body can readily use), the difference is staggering. It happened gradually, but it happened. I have not had this much stamina in years.

Yesterday I worked a full day, trained for almost two hours, cleaned my house, ran with my dog and kids and had some fun adult playtime with my girlfriend and I still had a little left in the tank.

Anyone else ever in this boat?

Been there, done that. Together w/ TRT, the b complex JFK shot i get every month - size of a race horse syringe - is what i credit with enabling me to feel like a full-fledged member of the land of the living.


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[pman42]

once in a while i geta boost of energy from B12 but I don't think I'm deficient. was when i was a vegan, though.

make sure to keep supplementing with methycobalamin because cyan when you're deficient can be counterproductive.

have you tried absolutely everything else for your GERD? DGL? mastic gum? zinc-carnosine? I'd be eating those like candy before i tried a proton pump inhibitor.

[Freepressright]

I'm afraid of DGL because licorice is estrogenic. I've tried about every kind of fancy enzyme and digestive aid to no avail.

I'm going to give ROH-10 a shot soon. I need to get the fuck off of theses PPI drugs. I know they aren't good for a person.

[weekend]

^most acid reducers are actually either estrogenic or antiandrogenic and have the potential to cause gyno...

- - - Updated - - -

Especially omeprazole

[Freepressright]

I never even thought of that because it never crossed my mind. Googled it and there are lots of reports that support what you're saying. I guess it's time to aggressively seek a different course of action.

[Freepressright]

Suffice to say I've spent the majority of the morning researching not only all the natural remedies for GERD that I haven't tried, but I've looked into all the complaints of sexual dysfunction and estrogen-like side effects surrounding PPI drugs. I stopped and picked up some Heartburn Free (ROH10) from Enzymatic Therapy on the way to work. It's a 20-day treatment and looks promising. I'm going to also grab some mastic gum and DGL. It can't be any worse than the estrogenic sides from PPI drugs. I'll just run a one-pump preventative dose of Sustain Alpha while I'm on the DGL.

Thanks for lighting a fire under my ass to get this done!

[nate3993]

Dam. That's tight. Glad you your pep back in your step. I tried Synthetek's B-12 for appetite but to no avail. They have some pretty dam good b-12 for cheap.
Lasts a while too since it's the timed release, but obviously you now have a script for it.

Idk if this would work, but maybe a refrigerated pro-biotic? I have IBS that comes and goes, literally, due to my Lyme disease and a probiotic knocks that shit out. I know we're experienceing different issues, but possibly restoring the natural flora in there might help. Metagenics probiotics are the absolute best I've ever used. Check a local health food store.

[pman42]

Also look into PepZinGI, a zinc-carnosine complex. that, mastic gum and DGL should knock it out. add the enzymatic probiotic and you've got a good stack goin there

[Freepressright]

Tell you what, though, the methyl B-12 is incredible. I can't go on enough about how human I feel now.

I also have 32 ampuoles of injectable B complex. My natural MD suggested daily methylcobalamin and one injection per week. But I've been feeling so well with the methyl-B that I haven't given myself another shot.

[Freepressright]

Regarding the ROH-10 (d-limonene) in the Enzymatic Therapy Heartburn Free - I've had orange burps since about an hour after taking it. It's kind of cool, actually.

I went ahead and took my PPI this morning because I've read that the ROH-10 can initially aggravate the reflux before helping it (kinda like Hawthorne raises BP before lowering it). I'm going to discontinue all PPI drugs next week.

The ROH-10 is taken every other day for 20 days and they say it is not needed again for six months, in most cases. Meantime, I'll get some DGL and mastic gum.

[weekend]

probiotics and avoiding cheeseburgers/pizza/fried food is helpful for me when I get heartburn from orals..

[pman42]

wow ROH-10 is a huge amount of d-limonene, nice

check out PepZinGi too, man, stuff is good.

[Freepressright]

Today is an off-day from the Heartburn Free. It's an EOD protocol. No orange burps today.

I have my fingers crossed that this stuff works.

[Enuke65]

What brand and dose of methyl b12 are you using?

[Freepressright]

Irwin Naturals Mega B Complex softgels with methylcobalamin and medium-chain triglycerides. It also has Bioperine for absorption enhancement.

$15.99 for two months worth.

Taken per label recommendation. Takes a couple weeks or so to start feeling the full effects.

[Freepressright]

Here's the breakdown:

Thiamine (as Thiamine Mononitrate) (B1) 30 mg 2,000%
Riboflavin (B2) 30 mg 1,765%
Niacin (as Niacinamide) (B3) 30 mg 150%
Vitamin B6 (as Pyridoxine Hydrochloride) 30 mg 1,500%
Folic Acid (B9) 400 mcg 100%
Vitamin B12 (as Methylcobalamin) 1,000 mcg 16,667%
Biotin (B7) 300 mcg 100%
Pantothenic Acid (as D-Calcium Pantothenate) (B5) 30 mg 300%
Medium Chain Triglyceride (MCT) Oil 455 mg †
N,N-Dimethylglycine (DMG) (B15) 30 mg †
BioPerine ComplexBioPerine® Black Pepper extract (95% piperine) (fruit), Ginger extract (5% gingerols) (root) 6 mg †

†Daily Value not established.

[Enuke65]

Thanks man, gonna have to check it out

[Haritec]

Resurrecting an old thread - but with some other info.

In regards to B vitamins - a lot of people have issues with Folate (as in poor absorption or biological pathways that are less than optimal). I notice that the B vitamin FPR is taking has folic acid -some people can't absorb that and convert it to the needed material which is Tetra Methyl Folate - for them the B-Vit has to contain TMF and not folic acid. For others, there are metabolic pathways that put them in need of folinic acid.

I recently sent a sample in for a complete genetic analysis at 23andme (23andme.com). They analysis for about 500,000 gene fragments for $99, and give you some reports on your genetics, whether you are a carrier for genetic diseases, how you react to various drugs and also some info about your ancestry. The interesting thing is you can then have your data analyzed at geneticgenie.com - and they give a full analysis of some of the major genes that affect how you use b-vitamins. You can also get more information about your genetics from Promethease.com and from MTHFRSupport.com. All of this stuff is time consuming but pretty fascinating - I am trying to figure my shit out. However, here are some samples of what I have found out.

I have dilated cardiomyopathy - it turns out I have defects in two genes that affect how the body prevents oxidative damage ( SuperOxide Dismutase) and these are correlated with cardiomyopathy. As a result - I should load up on anti-oxidants.

I have a defect in a gene that affects the bodies uses and uptake of Vitamin D - have to hit that up hard.

I have a gene that prevents me from recycling B12 - so my demand for B12 is especially high.

I have a gene that prevents me from converting methyl folate to folinic acid - and folinic acid is needed in other pathways. So I should supplement with folinic acid.

B vitamins are a huge part of the methylation pathways in the body - which deal with everything from processing estrogen to detoxing from drug use. Personally I have found this 23andme information useful in providing a direction for some nutritional supplementation. Some of it is just humorous - my wife's reply when I told here I was doubly negative in a gene that is related to empathy - "NO Shit Sherlock"