Using clomid and arimidex - need help for doses

So I started to use clomid and anastrozole since my T was too low (298) and my E2 too high (39). I started using 25mg of clomid in the morning ED and 0.25 of anastrozole ED in the morning too. I just saw on my other post that would be better to take anastrozole in the evening, before going to bed.

Also, since my cortisol is too high, I was wondering if I could take some hydrocortisone to rest the adrenals and block the excessive production of progesterone, since it was to high too. Today my doctor ordered and ultrasound from my thyroid and found a nodule so it must be out of whack too.

Since when is 39 too high? Sounds in range to me. Let your doc run his tests man. See what he can do for you, before you start looking into advice here. Exhaust your options..but I've never dealt with PFS.

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Originally Posted by tallstraw

Since when is 39 too high? Sounds in range to me. Let your doc run his tests man. See what he can do for you, before you start looking into advice here. Exhaust your options..but I've never dealt with PFS.

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The upper range was 40, so with the low T I believe 39 is too much. Anyway, I wonder where all that came from since m T is so low.

Another thing that I never found an explanation too is how did I get gyno symptoms from taking AI. That was before finasteride and I still don't understand. I was cycling T, deca and dianabol and a week after I started arimidex I began to have gyno issues which subsided when I took stanozolol.

You have an overly active aromatase enzyme, it is very common in people with finasteride issues. If you are looking to get a more favourable T:E ratio then I'd ditch the clomid, it's a horrible drug when taken for any extended time. Look into using herbs to raise your T rather than a pharmaceutical, and only if that doesn't lead to improvement then consider an AI down the road. My advice is to exhaust all natural options first... A toxic Pharmaceutical got you into this mess in the first place.

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Originally Posted by Swill

You have an overly active aromatase enzyme, it is very common in people with finasteride issues. If you are looking to get a more favourable T:E ratio then I'd ditch the clomid, it's a horrible drug when taken for any extended time. Look into using herbs to raise your T rather than a pharmaceutical, and only if that doesn't lead to improvement then consider an AI down the road. My advice is to exhaust all natural options first... A toxic Pharmaceutical got you into this mess in the first place.

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But how could it get more active while taking arimidex and not before, while I was taking all those roids? This was before fin. I'm taking herbs, but my T kept falling. I think I have a problem in the adrenals and that gyno might have been from high progesterone. I'm thinking about going on roids again to see how my body reacts since I know how it is supposed to react.

You answered your own question with that statement... That was before fin. This is not your typical steroid use shut down.

I know it isn't, but the question is: how much of this is hormone imbalance?

TSH 1,3 [0,45 - 4,5] mUI/L
T4 7,9 [4,5 - 12,0] microg/dL
T3 111 [70 - 200] ng/dL
E2 3,9 [0,8 - 4,3] ng/dL
PROGESTERONE 112 [20 - 90] ng/dL
CALCIUM ION 1,32 [1,11 - 1,40] mmol/L
25 HIDROXI‐VITAMIN D (suplementing with 5000 ui for a couple days): 29 [30 - 60] ng/mL
PTH: 27 [10 - 65] pg/mL
ADH 14,9 [1,8 - 23,2] ng/dL
ANDROSTENEDIONA 91 [30 a 180] ng/dL
TESTOSTERONE TOTAL 536 [240 - 816] ng/dL
CORTISOL FREE : 185,6 [4,2 - 60,0] microg/24h
CORTISONE FREE: 368,3 [17 - 141] microg/24h
RELATION CORTISOL/CORTISONE: 0,50 [0,11 a 0,67]


This isn't the last one, but I was already in the crash (still could sleep thought)

From the last one I got this:

ALBUMIN: 4,1 [3,2 - 4,8] g/dL
LH: 1,00 [1.5 - 9.3] mIU/mL
FSH: 2,2 [1,4 - 18,1] mIU/mL
ESTRADIOL 40,3 [0 - 39,8] pg/mL
TESTOSTERONE TOTAL 298,0 [241 - 827] ng/dL
TESTOSTERONE FREE: 0,233 nmol/L [0.118 - 0.853]
67,15 pg/mL [34,01 - 245,82]
SHBG: 25,8 nmol/L [10 A 57] nmol/L
CORTISOL SALIVA ( 23 pm ): 11.47 nmol/L [NO REF]

Progesterone is high..but myoney is on prolactin being the culprit. It's something a lot of people don't take into account..even on an AI I had sensitive nips..had to nuke my estrogen to get it to go away which wasn't a solution...once I used prami e3d, for 2 weeks I had no issues and haven't had any since.

I had it checked, but it was mid range. Is selegiline a good choice to lower it too? What kind of issues should I expect from pramim? Dopamine desensibilization?

No no no, I'm not advocating you to self treat. Stick with your doc run through his treatment and see how you fare. See what he can do for you, if nothing works..start looking then.

Apparently you're not aware of how the doctors deal with this. If it's in range, it's in range, doesn't matter how close to the limits. If it's out of range it's just floating and means nothing, so they send me to the psychiatrist. I'm here humbly asking for help because doctors are to close minded and don't like these whole "optimization" approach.

Did you have prolactin tested?

Here is some info about the ideal estrogen range you are just above it: Ideal Estrogen Level

I had, just can't find I right now. Prolactin was mid range.

SDHEA - 601.00 ug/dL (80 - 560) ug/dL

PROGESTERONA - 1.56 ng/mL (0.28 - 1.22) ng/mL

THYROID PEROXYDASE ANTI BODIES <10.00 UI/mL < 35 UI/mL

SERUM CORTISOL MORNING - 28.70 ug/dL (5 - 25) ug/dL

TSH - ULTRASSENSIVEL 0.79 uIU/mL

TESTOSTERONE TOTAL 859.0 ng/dL (160-726 ng/dL) after clomid restart

TGP - 57 U/L ( 21 - 72) U/L

TGO - 38 U/L (17 - 59) U/L

GAMAGLUTAMILTRANSFERASE 35 U/L

DESIDROGENASE LACTICA 394 U/L (313 - 618) U/L

TRIGLICERIDEOS 52 mg/dL < 150 mg/dL

COLESTEROL HDL 52 mg/dL > 45 mg/dL

COLESTEROL 139 mg/dL < 200 mg/dL

GLUCOSE FASTING 91 mg/dL (74 - 100) mg/dL

VHS (1 Hour) 5 mm (0 a 15) mm

HEMOGRAMA

ERITROGRAMA

ERITROCITOS 5.24 milhoes/mm3
HEMOGLOBINA 15.9 g/dL
HEMATOCRITO 46.9 %
VCM 89.5 fl
HCM 30.3 pg
CHCM 33.9 g/gL
RDW 13.0 %
OBSERVACOES Sem particularidades
PLAQUETAS 143.000 /mm3 150.000 - 400.000/mm3

LEUCOGRAMA

RELATIVO (%) (MIL/MM3) VR (%) VR (MIL/MM3)
LEUCOCITOS 7.000
PROMIELOCITOS 0 0
MIELOCITOS 0 0
METAMIELOCITOS 0 0
BASTONESTES 1 70
SEGMENTADOS 48 3360
EOSINOFILOS 4 280
BASOFILOS 0 0
LINFOCITOS 36 2520
MONOCITOS 11 770
PLASMOCITOS 0 0
BLASTOS 0 0


Come on guys, any inputs? Seems like my adrenals are putting on a lot of hormones. Does that explain why I'm losing so much muscle? I also think this clomid restart shoot my estrogen through the roof since I'm having gyno symptoms. What's the next step here?
I developed a very oily scalp and face. Fatigue, anxiety, brain fog, everything is constant. I wonder if the high cortisol is making my blood vessel contract leading to poor blood flow to the brain.

Like I said on another post, I'm skeptical that all this was finasteride related. I did two steroid cycles in the past and no blood work after. In my second round I got some problems with deca and gyno, so I spend almost a year trying some gyno reversal protocols. I believe I was already out of balance and propecia was just the final touch. Shouldn't even been posting on the PFS section maybe.

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Originally Posted by ToniBR

SDHEA - 601.00 ug/dL (80 - 560) ug/dL

PROGESTERONA - 1.56 ng/mL (0.28 - 1.22) ng/mL

THYROID PEROXYDASE ANTI BODIES <10.00 UI/mL < 35 UI/mL

SERUM CORTISOL MORNING - 28.70 ug/dL (5 - 25) ug/dL

TSH - ULTRASSENSIVEL 0.79 uIU/mL

TESTOSTERONE TOTAL 859.0 ng/dL (160-726 ng/dL) after clomid restart

TGP - 57 U/L ( 21 - 72) U/L

TGO - 38 U/L (17 - 59) U/L

GAMAGLUTAMILTRANSFERASE 35 U/L

DESIDROGENASE LACTICA 394 U/L (313 - 618) U/L

TRIGLICERIDEOS 52 mg/dL < 150 mg/dL

COLESTEROL HDL 52 mg/dL > 45 mg/dL

COLESTEROL 139 mg/dL < 200 mg/dL

GLUCOSE FASTING 91 mg/dL (74 - 100) mg/dL

VHS (1 Hour) 5 mm (0 a 15) mm

HEMOGRAMA

ERITROGRAMA

ERITROCITOS 5.24 milhoes/mm3
HEMOGLOBINA 15.9 g/dL
HEMATOCRITO 46.9 %
VCM 89.5 fl
HCM 30.3 pg
CHCM 33.9 g/gL
RDW 13.0 %
OBSERVACOES Sem particularidades
PLAQUETAS 143.000 /mm3 150.000 - 400.000/mm3

LEUCOGRAMA

RELATIVO (%) (MIL/MM3) VR (%) VR (MIL/MM3)
LEUCOCITOS 7.000
PROMIELOCITOS 0 0
MIELOCITOS 0 0
METAMIELOCITOS 0 0
BASTONESTES 1 70
SEGMENTADOS 48 3360
EOSINOFILOS 4 280
BASOFILOS 0 0
LINFOCITOS 36 2520
MONOCITOS 11 770
PLASMOCITOS 0 0
BLASTOS 0 0


Come on guys, any inputs? Seems like my adrenals are putting on a lot of hormones. Does that explain why I'm losing so much muscle? I also think this clomid restart shoot my estrogen through the roof since I'm having gyno symptoms. What's the next step here?
I developed a very oily scalp and face. Fatigue, anxiety, brain fog, everything is constant. I wonder if the high cortisol is making my blood vessel contract leading to poor blood flow to the brain.

Like I said on another post, I'm skeptical that all this was finasteride related. I did two steroid cycles in the past and no blood work after. In my second round I got some problems with deca and gyno, so I spend almost a year trying some gyno reversal protocols. I believe I was already out of balance and propecia was just the final touch. Shouldn't even been posting on the PFS section maybe.

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I think your problems probably are finasteride related given the breadth of them. I personally wouldn't touch Clomid, in spite of the fact it works well for bodybuilders who need a nudge to restart after a cycle, for the vast majority of people with finasteride issues it causes more problems than the worth of it; I felt my worst mentally, emotionally and sexually when experimenting with this drug... it raises Total T levels but sends a host of other things batshit crazy in my experience.

IMO You want to get off the pharma for now and see how your body responds to clean diet and exercise (mostly resistance weight training) for a few months before deciding where to go from here. The fact that you have previously lifted is a positive as I assume you know what you are doing in a gym. Get off the meds, Eat well, sleep well, train well and then evaluate from there in 3/4 months.

Why didn't you get your E or SHBG levels tested with that round of bloods? Clomid can do screwy things with your E levels, absolutely. Also, it bumps my prolactin (but it doesn't do that to everyone with fin issues).

Quote:

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Originally Posted by Swill

I think your problems probably are finasteride related given the breadth of them. I personally wouldn't touch Clomid, in spite of the fact it works well for bodybuilders who need a nudge to restart after a cycle, for the vast majority of people with finasteride issues it causes more problems than the worth of it; I felt my worst mentally, emotionally and sexually when experimenting with this drug... it raises Total T levels but sends a host of other things batshit crazy in my experience.

IMO You want to get off the pharma for now and see how your body responds to clean diet and exercise (mostly resistance weight training) for a few months before deciding where to go from here. The fact that you have previously lifted is a positive as I assume you know what you are doing in a gym. Get off the meds, Eat well, sleep well, train well and then evaluate from there in 3/4 months.

Why didn't you get your E or SHBG levels tested with that round of bloods? Clomid can do screwy things with your E levels, absolutely. Also, it bumps my prolactin (but it doesn't do that to everyone with fin issues).

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I didn't order sbhg and e2 because my doctor didn't want to and here in Brazil the doctor need to order or else the insurance won't cover it. I don't think it's too relevant since obviously I need to, somehow, do something about my adrenals before. I'll get a full panel soon and I'm off adex and clomid for now.

What would be my best natural ways to lower my estradiol without rebound?