@
DrivenToRecover As our resident expert on heat/cold exposure, do you have any insights re: vitamin E supplementation timing related to heat exposure? One of the links you had sent out a while ago included some information from Dr. Rhonda Patrick (our adjunct expert :)) which mentions that E supplementation may interfere with mitochondrial biogenesis from the heat stress. I haven't been able to find more detail on this yet, but I have not been supplementing with E on days I sauna for the time being. Thoughts?
From Dr. Rhonda Patrick:
"The other thing that happens in terms of mitochondrial biogenesis and the reason why it occurs when you're exposed to heat, is that heat itself is a stressor on the body and it creates reactive oxygen species (ROS).
ROS are also generated when you exercise; when you're causing your body to work more. These ROS act as a signaling molecule to make more mitochondria.
If you exercise and take a supplemental vitamin E or something that can sort of soak up the ROS, you can negate some of the positive benefits from exercise because you are now not getting those signaling molecules saying, 'Hey, we've got stress here. Let's make more mitochondria to deal with the stress.'
It's really important that you actually have some of that stress. That's part of the mechanism by which it increases mitochondrial biogenesis."