Anybody here deal with depression?

[Jelisej]

if it wasnt for a dog i wouldve killed myself when i was 19. now if i didnt have kids i would have probably killed myself. between my fucked up life experiences and the chemicals in my brain (nature/nurture) im pretty screwed up. i pray to always be in recovery because my life is overall pretty good but its a lot of shit i dont feel like doing at times because im tired/depressed. DBT, CBT, support groups, the gym, just having hobbies and me time and appropriate rest time, writing and talking with people. spilling my shit of BBing forums lol i gotta go do shit i dont want to now so ill post more later maybe

Chemicals in brain (neurotransmitters) are difficult issue, but it can be dealt with.

Sometimes just sorting out hormonal profile is enough- which is sometimes just improving lifestyle, tough most of times its more than that. It depends what the problem is, IMO most of depressions caused by chemicals are connected with adrenals- or low adrenal hormone levels, sometimes E2 can be issue as it has very strong effect on serotonin- so when too much E2 is there person tends to overact be abnormally sensitive (similar to women on PMS) on other hand when its too low it could present itself with similar symptoms or it could be plain depression where one just want to put blanket over top of the head and stay in bed (low serotonine activity),
also if cortisol is low- body will try to compensate with adrenalin(s) which has downside, also it leads to depletion of pregnenolone which is powerfull neurosteroid and has neuroprotective properties....
Low dopamine levels (sometimes because high prolactin) has it symptoms etc...

[silverstrand]

Chemicals in brain (neurotransmitters) are difficult issue, but it can be dealt with.

Sometimes just sorting out hormonal profile is enough- which is sometimes just improving lifestyle, tough most of times its more than that. It depends what the problem is, IMO most of depressions caused by chemicals are connected with adrenals- or low adrenal hormone levels, sometimes E2 can be issue as it has very strong effect on serotonin- so when too much E2 is there person tends to overact be abnormally sensitive (similar to women on PMS) on other hand when its too low it could present itself with similar symptoms or it could be plain depression where one just want to put blanket over top of the head and stay in bed (low serotonine activity),
also if cortisol is low- body will try to compensate with adrenalin(s) which has downside, also it leads to depletion of pregnenolone which is powerfull neurosteroid and has neuroprotective properties....
Low dopamine levels (sometimes because high prolactin) has it symptoms etc...

I'm getting this idea that my adrenals might be compensating for low cortisol with adrenalins, depleting my pregnenolone as you say and causing my insomnia. This is guess work at this time without blookwork but my symptoms are very similar. I'm thinking 20 to 30 mg of Preg sublingual might be the answer or same amount 20 to 30 mg split between sublingual and transdermal? I dont want to do all transdermal because of the potential for high conversion to Progesterone that might cause suppression of DHT but then again, it might not even be an issue as Preg will work to balance out all hormones.