thoughts on progesterone / pregnenolone

[Mojo]

Is applying andro a bandaid fix or will it change the way receptors function in the longterm?

[Karlucchi]

Any kind of exogenous hormone use will change epigenetic expression. Androsterone should change the expression in the long run for the better. But not EpiAndrosterone.

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Question about this statement. Using UltraHard (Epi and Andro) would still downregulate AR receptors correct? Just not help with the GABAA receptors as much as just Androsterone alone would?