I can't speak from a PFS standpoint, but iconic formulations just recently released
Neuro Melatonin topical - the issue with melatonin is the extremely short half life (around 30 minutes)...trandermal delivery slowly releases melatonin into the bloodstream over about 6 hours, to not just get you to sleep, but to keep you asleep.
There are some studies on the use of td melatonin to aid in managing jet lag, or for those who switch to evening shifts and need to sleep during the day.
https://iconicformulations.com/colle...euro-melatonin