Transdermal Epi

[campcoll88]

Already have some Transdermal h-drol... was thinking of making some TD epi with iron legions salvo.

Question is, would this significantly reduce the toxicity of epi?

[SoCal-Nutrition]

I'm curious...I don't understand the point of running methylated steroids transdermally.

is there really a benefit here?

[campcoll88]

really cheap raw powders (about twice as much bang for buck), I dont feel like capping (much easier to dump in iron legion salvo) and avoid first pass metabolism which I think would reduce impact on liver but IDK.

Would TD significantly reduce its impact on the liver? Epi is cheap and effective so why not

[campcoll88]

Was going to use it with a nonmethyl run of Trestobol and 5-alpha test and want to keep it liver friendly.

[romangod]

really cheap raw powders (about twice as much bang for buck), I dont feel like capping (much easier to dump in iron legion salvo) and avoid first pass metabolism which I think would reduce impact on liver but IDK.

Would TD significantly reduce its impact on the liver? Epi is cheap and effective so why not

Some feedback here would be AWESOME!!

[LBC-83]

Molecule size small enough to pass transdermally?

[burlyman30]

If it is methylated, i see no advantage to TD application except for the price of raw powders.

Healthwise, the methylation also passes through the liver once it is in the system, so no advantage there.

Methylation increases absorption quite a bit over not methylated (orally) so not sure that TD would be an advantage over oral administration.

Non-methyls do well in TD application because they are typically poorly absorbed (no methylation=destruction as it passes through the liver).

Some compounds are actually metabolized differently and/or better with TD application. Dermacrine and 1-T were two that would fit this category. Trenazone/dienazone also. Note that none of the above are methylated.

[nate3993]

trest is methyl and works well as a td, but i guess that's the exception.

[burlyman30]

trest is methyl and works well as a td, but i guess that's the exception.

Not saying a methyl won't work, but just that I don't see any advantage.

[Enuke65]

trest is methyl and works well as a td, but i guess that's the exception.

Trest is also not 17aa