Interesting DHEA Article

[Strong_Guy]

An interesting read I found on DHEA:

DHEA

Some stuff people may already know, others may not.

[Sperwer]

Nice find

[Strong_Guy]

Another good read:

Hormone CPC #1: DHEA

[silverstrand]

Another good read:

Hormone CPC #1: DHEA

This is a great read:

I've copied an paste some info I found most interesting:

"inflammatory cytokines as the main causes of their progression. These chemicals are destructive to cell membrane signaling, cellular nuclear processessing signaling, and cytosolic signaling. They have particularly devastating affects on the steroid hormone receptors and the receptors of both arms of the immune system."

"We have known from Cutolo’s 2000 study that most adrenal hormones (like DHEA) are very low prior to development of the full blown disease."

"DHEA has been shown to prevent chronic inflammation and it slows the abberant signaling that is commonly found in the immune system when it is turned on by any pathogen, self or foreign. DHEA is particularly helpful in limiting IL-6 and TNF alpha in both disease propagation and in normal human aging."

"Yen showed the remarkable effect of a low dose of DHEA (50 mgs a day for 6 months) restoring DHEA levels in men and women while dramatically improving their perceived physical and psychological well being for both sexes."

"DHEA was the easiest way to elevate IGF 1 levels to improve growth hormone secretion without expensive replacement"

"I used DHEA cream to help rid myself of the nasty red stretch marks from being morbidly obese. I do not have one red stretch mark left on my body." (If you get big enough to start getting stretch marks around the arms/Chest - this could be a good tool to get rid of that)

[SoCal-Nutrition]

man, for a moment I thought Sperwer was back...

Great article though! Great timing for the new Alpha Gainz DHEA-TD

[Cdsnuts]

What would you guys run the new DHEA TD at? 200 -300mg if you were gonna do a stand alone run?

[Strong_Guy]

What would you guys run the new DHEA TD at? 200 -300mg if you were gonna do a stand alone run?

I would probably have to do a little trial-and-error to figure that out, since I've never ran it as a true stand alone. Dermacrine at 6 pumps was always my sweet spot which would put dhea at about 86 mg but there are other things in there too. I'd probably start out at about 100 mg and work my way up as needed.

[silverstrand]

I would probably have to do a little trial-and-error to figure that out, since I've never ran it as a true stand alone. Dermacrine at 6 pumps was always my sweet spot which would put dhea at about 86 mg but there are other things in there too. I'd probably start out at about 100 mg and work my way up as needed.

From the reading material, it would appear the most beneficial amount is right where you say - at roughly 100mg per day. Also, it's advised to use a little pregenalone along with it. This is exactly the formulation of AndroDrive V3. There looks to be no suppression on Andrenal function with these two hormones whatsoever. When talking with Eric, he said that DHEA can be suppressive to HPTA but I cant remember why - I'd love for him to comment. Since DHEA can convert to estrogen, it might be a good idea to use a mild aromatase inhibitor like DHT or Reserveratrol. Appearantly, DHEA is the most abundant circulating hormone in the body so if the andrenals are NOT functioning properly, the body can be deficient. Cortisol/DHEA ratio is important as these two fight for dominance in the body. I researching this a possible reason for my sleep issues as my DHEA is low.


DHEA - Link

These are some quotes from the link above.

"The ideal anti-aging strategy is to supplement both DHEA and its precursor, pregnenolone (which I'll discuss in a bit). Since your body will convert some of the pregnenolone to DHEA, any increase in the dosage of pregnenolone may result in a higher level of DHEA. (The opposite does not hold true, however: Your body doesn't convert DHEA to pregnenolone.) The rate at which pregnenolone is converted to DHEA varies from one person to the next. So monitor levels of both hormones every few months and adjust your doses until both are within their respective desired ranges."

"Many hormones, including cortisol and thyroid hormone, are controlled by a feedback loop system that shuts off production when levels get high. Not so with DHEA and pregnenolone: Your body will keep right on making these hormones in the same amounts as before you began supplementation. In other words, taking supplements of DHEA and pregnenolone won't suppress your body's production of these hormones or cause adrenal atrophy. "

[Jelisej]

DHEA is beneficial, but I would say supplementing with pregnenolone is better strategy or if DHEA(s) levels dont top up well DHEA can be added, also excessive amount of DHEA gets converted to E2 a lot in men, ironically in women it gets coverted to testosterone.

[silverstrand]

also excessive amount of DHEA gets converted to E2 a lot in men, ironically in women it gets coverted to testosterone.

I'm guessing this is why all the literature I read for men supplimenting with DHEA are using dosages of 25 to 100 mgs per day. At these doses, do you see E2 as being an issue? What dosage range do you think E2 would become a problem on DHEA?