Plasma fibrinolytic activity following oral anabolic steroid therapy.
Plasma fibrinolytic activity following... [Thromb Diath Haemorrh. 1975] - PubMed - NCBIWalker ID, Davidson JF, Young P, Conkie JA.
Abstract
Six anabolic steroids were assessed for their ability to enhance plasma fibrinolytic activity in males with ischaemic heart disease. Five 17alpha-alkylated steroids (Ethyloestrenol, Norethandrolone, Methandienone, Methylandrostenediol and Oxymetholone) were examined and all produced a significant increase in plasma plasminogen activator as measured by the euglobulin lysis time. The only non-17alpha-alkylated steroid studied (Methenolone acetate) failed to enhance fibrinolysis. The 17alpha-alkylated steroids studied all deserve more detailed evaluation of their long term effects on plasma fibrinolytic activity.