That thought crossed my mind, but I have cycled Dermacrine many, many times; solo, stacked with other PHs, and for extended lengths of time at fairly high doses (5-6 pumps). Never had any adverse effects, only felt great. Also, my first three weeks of this particular cycle were with Derm only; didn't feel anxious or weird at all, just when I started the Epi.
I'm done though, scrapping the Epi altogether, it's not worth any potential problems to me. I'm going to finish out my last half of this cycle with Dermacrine and try some of my newly acquired Ultra-Stano instead.