Raw powders and how to utilize them

[Enuke65]

Snagged a few grams of powders when everyone cleared out of their stock and am trying to figure out how to best utilize them

Say for example 3 grams of d-plex powder.

Would it be worth it to try and brew into an oil or somehow manage to cap it or put it into an oil suspension.

I forgot how little powder actually makes up a few grams, makes it difficult to cap.

[Spank]

Capping SUPPLEMENTS
By: SV-1


I will follow this article with another one about how to properly weigh and to properly mix the Supplement powders together. I know the first one deals with weighing the powders, but the mixing the supplement powders is just as important!

Things you will need to make your Supplement capsules.

1. A capping device and empty gel caps. The two most popular capping devices are the "Cap-M-Quick" and "The Capsule Machine". The cap-m-quick does 50 caps at a time but you have to manually join the caps by hand. The capsule machine only does 24 caps at a time but automatically joins them for you. Both of these devices can be purchased to use either size "0" or "00" caps (size "0" caps are smaller than size "00"). I prefer the capsule machine and size "0" caps, but either device in either size is fine.

2. A scale to weigh the powders you'll be using to make your caps. I recommend either the Palmscale 5.0 which is accurate to 0.1g and has a capacity of 200g (cost approx $60), or the GemPro-50 which is accurate to 0.002g and has a capacity of 10g (cost approx $150).

3. The powdered version of the supplement that you plan on capping. However compounds such as Clen, T3, Femara and Arimidex should never be capped because of their small dose amounts and the inherent inaccuracies of the capping process.

4. A powdered filler that will be used to take up the space in the caps that the active compound doesn't. Almost anything can be used as a filler, protein Powder, Baking Soda (Sodium Bicarbonate), Corn Starch, Flour, creatine, Lactose, glutamine, etc.

5. A mortar and pestle to thoroughly mix the active compound and filler together. Many compounding pharmacies use a mortar and pestle to mix their ingredients together for capping and if it's good enough for them it's good enough for me.

Now that we have everything necessary to make our caps here's how we do it. For the example below I'll use the capsule machine to make 48 caps with 100mg of Aspirin (active compound) and Baking Soda (filler).

1. Load 24 empty caps into the capsule machine, then fill all 24 caps with Baking Soda (tamping powder if final caps will be tamped).

2. Empty all the Baking Soda out of the capsule machine and weigh it. Total weight = 17,160mg

3. Divide that weight (17,160mg) by the number of capsules (24) to get the total weight per cap. 17,160mg / 24 = 715mg a cap.

4. Repeat these steps with the Aspirin powder. Total weight = 11,760mg / 24 = 490mg a cap.

5. Now we need to figure out the ratio of Aspirin to Baking Soda.

100mg Aspirin = Unknown mg of Baking Soda

490mg Aspirin = 715mg Baking Soda

(100mg Aspirin x 715mg Baking Soda) / 490mg Aspirin = 146mg of Baking Soda (this is the Unknown mg of Baking Soda, and how much must be removed to make space for 100mg of Aspirin)

715mg Baking Soda - 146mg = 569mg Baking Soda (this is how much Baking Soda to use per cap)

569mg Baking Soda x 48 caps = 27,312mg Baking Soda

100mg Aspirin x 48 caps = 4800mg Aspirin

So to make 48 100mg Aspirin caps we need 4800mg of Aspirin powder and 27,312mg of Baking Soda.

This is where the simpler methods fail and give inaccurate results. As the chart below shows, different compounds (like Aspirin and Baking Soda (Sodium Bicarbonate)) weigh different amounts for the same volume. If we had simply subtracted 100mg from the Baking Soda we would not have had properly dosed caps, because to fit in 100mg of Aspirin we needed to subtract 146mg of Baking Soda.

Now that we know how much active compound and filler to use (Aspirin and Baking Soda) we need to mix them together. To do this we'll use a mortar and pestle with the geometric dilution method, which was introduced to me by pharmguy24 on AU. What's the geometric dilution method you ask? It's a method used when a small amount of powder needs to be *thoroughly* mixed with a larger amount of powder. To do this you mix all of the smaller powder with an approximately equal amount of the larger powder, this blend is called "mix 1". Then combine all of your "mix 1" with an equal amount of the larger powder and blend again, this is "mix 2". Keep going like this until all the powders have been mixed together.

So we place all of the Aspirin powder (the smaller amount of the two different powders) in the mortar and add an equal amount of the Baking Soda (approximately 4800mg), then blend them together with the pestle for a couple of minutes. This combination is our mix 1, and it is now 9600mg (4800mg Aspirin + 4800mg Baking Soda). After it's been blended for a few minutes add an equal amount of Baking Soda (9800mg) to your mix 1 and blend for a couple more minutes. This combination is our mix 2 and is 19,200mg (9800mg from mix 1 + 9800mg Baking Soda). After it's been blended for a few minutes add the remaining Baking Soda (12912mg) to your mix 2 and blend for a couple more minutes.

Why go to this extra trouble? Because even though we know the amounts of Aspirin and Baking Soda we're using are dead on, our caps will not be dosed properly if the powders are not mixed together very thoroughly.



Now we're ready to make our caps.

1. Load both the base and top of the capsule machine with the empty gel caps (the bottom should already be loaded from weighing the powder for mixing).

2. Place the base on its stand and pour the mixed powder over the empty caps, then spread it around using the supplied plastic card so all the caps are filled.

2a. Optional: At this point you can tamp the powder down and add more powder to the caps increasing the amount they can hold. But because what we want to cap fits fine without doing that we didn't calculate for it and wont be doing it.

3. Attach the top of the capsule machine (which contains the other halves of the caps) to the base.

4. Remove the capsule machine from its stand and press it down on your work surface applying even pressure to join the caps.

5. Remove the top from the capsule machine and press against the spring loaded plate on its back to eject the finished caps.

6. Repeat these steps until all your caps are made.

Follow these guidelines and you too can make your own accurately dosed caps.

This information might be useful for you.
I have not tried this yet or a liquid suspension
I have read that when mixing powders it is important to choose a filler that has a similar particulate size and density (Weight/volume)
I have also read that some individuals find it helpful to mix red jello powder into their powder really well before dilution to get a better visual on how well the final mixture is diluted.

Let me know how this turns out because I will need to do this in a couple of months. Maybe take some pics, scrub the EXIF data ("The Exif format has standard tags for location information. As of 2014 many cameras and most mobile phones have a built-in GPS receiver that stores the location information in the Exif header when a picture is taken.") and post them up when you're finished for a diy.

[Enuke65]

Super informative guide man, thanks for that

[hossam]

i really needed this detailed information, thanks man

[noneck]

Instructions For Capping Powders
by HarveyB

While cap-m-quik machines are standard, I personally prefer another device from called the "Capping machine." The reason is this: the capping machine will apply capsules tops automatically in a one-motion press of the top tray, instead of having to hand-apply each capsule top one at a time with the cap-m-quik. Be sure to practice a lot of times first so you'll get the smooth, even pressure motion down. Otherwise you'll inevitably crush and break a few capsules. Hint: don't overfill them (too much filler squeezes rhe sides outward, making them harder to cap properly).

You will need a cap-m-quick or a capping machine. Each have their own advantages, so your call I will include instructions for each.

http://www.finakit.8k.com/catalog.html
Capsule Machines | Empty Gelatin Capsules | Empty Vegetable Capsules

You'll need a precise--PRECISE--scale.

OK say we are going to make 50 caps, this would be with the cap-m-quick machine.

1: Fill one cap with filler (probably want 00 size), corn starch works nicely for winny, or you can use protein powder, creatine, sugar, etc. only use the bottom half of the cap.

2: Weigh the cap, say it came out to .40 gram, you take .40 multiplied by 50 (number of caps you want) you get 20 grams.

Next you figure out your mg concentration you want of each pill, we will say you want 50mg/ml. 50mg multiplied by 50 = 2500mg or 2.5 grams.

So you take your total amount of fill 20 grams subtract your hormone, 20g subtract 2.5g = equals 17.5g of your filler.

3: Put your filler and hormone in a shaker or a bag, and shake very well. It may not be 100% accuate, but you shouldn't be off by too much, 10% max.

4: Fill the machine with your caps, pour powder over it, use the spreader, and follow the directions of the machine for capping powder.

5: Cap. Expect to lose a small amount of powder as you individually cap each capsule; this is neglibile.

You now have 50 caps very close to 50 mgs each.


OK say we are going to make 24 caps, this would be with the capping machine.

1: Fill one cap with filler (probably want 00 size), corn starch works nicely for winny, or you can use protein powder, creatine, sugar, etc. only use the bottom half of the cap.

2: Weigh the cap, say it came out to .40 gram, you take .40 multiplied by 24 (number of caps you want) you get 9.6 grams.

Next you figure out your mg concentration you want of each pill, we will say you want 50mg/ml. 50mg multiplied by 24 = 1200mg or 1.2 grams.

So you take your total amount of fill 9.6 grams subtract your hormone, 9.6g subtract 1.2g = equals 8.4g of your filler.

3: Put your filler and hormone in a shaker or a bag, and shake very well. It may not be 100% accuate, but you shouldn't be off by too much, 10% max.

4: Fill the machine with your caps, pour powder over it, use the spreader, and follow the directions of the machine for capping powder.

5: Cap. Expect to lose a small amount of powder as you individually cap each capsule; this is neglibile.

You now have 24 caps very close to 50 mgs each.