Quote Originally Posted by Cdsnuts View Post
E being a potent 5a reductase enzyme? That doesn't sound quite right.
It's a reductase inhibitor according to the studies I've read.

Effects of sex steroids on skin 5 alpha-reductase activity in vitro. - PubMed - NCBI
[Effect of estradiol on 5 alpha-reductase activity in osteoblast-li... - PubMed - NCBI

I'd be a little wary of DIM, English. I've read a few studies that suggest it binds to the same receptors DHT does, the studies I found were only in prostate cancer cells however.