Sustain alpha is back?!?!

[Bucks]

Pretty sure it was


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[5 alpha victim]

My main reason for loving topical SA, besides the fact there's universal agreement that it worked and worked extremely well, is that it will put acne into long-term remission. I had severe cystic acne on my back. Sustain Alpha cleared it up and it stayed gone for a year.

I shared this news with others on the PP forums, who followed suit and had the same results. Then I found some studies pointing to how effective transdermal resveratrol is at treating acne. This is great news.

Hey man,

What is it about the Res in the sustain alphs that helps acne?

Does that mean Res has some type of inhibiter effect on DHT levels?

Sustain alpha was one of the first things I tried after crashing from a DHT inhibiter and to be honest made me feel good. The stuff was awesome.

But I'm wondering if I should be taking it now if it is a DHT inhibiter.

I also remember PP charging approx 75 per bottle if I rember correctly so this price is real good

[BBG]

The resveratrol in Sustain Alpha literally inhibits the acne causing bacteria: Resveratrol Demonstrates Antimicrobial Effects Against Propionibacterium acnes In Vitro - Springer

[Cdsnuts]

Hey man,

What is it about the Res in the sustain alphs that helps acne?

Does that mean Res has some type of inhibiter effect on DHT levels?

Sustain alpha was one of the first things I tried after crashing from a DHT inhibiter and to be honest made me feel good. The stuff was awesome.

But I'm wondering if I should be taking it now if it is a DHT inhibiter.

I also remember PP charging approx 75 per bottle if I rember correctly so this price is real good

I'll say it yet again. Res/sustain, etc...IS NOT a DHT inhibitor.

[entropy]

I'll say it yet again. Res/sustain, etc...IS NOT a DHT inhibitor.

Lol cd, are you absolutely sure? We've only had to tell people about five million times so far.

[Bam24]

I'll say it yet again. Res/sustain, etc...IS NOT a DHT inhibitor.

Is there a need for any kind of e control with the SA?? Didn't know if it converts or any e sides would happen? Can it be taken by itself ? Bout to grab some just making sure first.
Thanks in advance


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[entropy]

Is there a need for any kind of e control with the SA?? Didn't know if it converts or any e sides would happen? Can it be taken by itself ? Bout to grab some just making sure first.
Thanks in advance


Sent from my iPhone using Tapatalk

Res is actually a serm and an ai

[BBG]

In case you guys wanted to look at the many studies that Primordial used to use to promote Sustain Alpha:

1. Resveratrol in Cardioprotection: A Therapeutic Promise of Alternative Medicine
Dipak K. Das et al.
Mol. Interv., Feb 2006; 6: 36 - 47.


2. The Red Wine Polyphenol Resveratrol Displays Bilevel Inhibition on Aromatase in Breast Cancer Cells
Yun Wang, et al.
Toxicol. Sci., Jul 2006; 92: 71 - 77.

3. trans-Resveratrol, a Natural Antioxidant from Grapes, Increases Sperm Output in Healthy Rats M. Em?*lia Juan, et al.
J. Nutr., Apr 2005; 135: 757 - 760

4. trans-Resveratrol relaxes the corpus cavernosum ex vivo and enhances testosterone levels and sperm quality in vivo.
S Shin, et al.
Arch Pharm Res, Jan 2008; 31(1): 83-7.

5. Inhibition of human estrogen synthetase (aromatase) by flavones
JT Kellis, Jr et al.
Science, Sep 1984; 225: 1032 - 1034.

6. Drug/substance reversal effects of a novel trisubstituted benzoflavone moiety (BZF) isolated from Passiflora incarnata Linn. - a brief perspective
KAMALDEEP DHAWAN et al.
Addiction Biology (December 2003) 8, 379 - 386

7. Prevention of chronic alcohol and nicotine-induced azospermia, sterility and decreased libido, by a novel tri-substituted benzoflavone moiety from Passiflora incarnata Linneaus in healthy male rats.
K Dhawan and et al.
Life Sci, Nov 2002; 71(26): 3059-69.

8. Molecular basis of the inhibition of human aromatase (estrogen synthetase) by flavone and isoflavone phytoestrogens: A site-directed mutagenesis study.
Kao YC, et al.
Environ Health Perspect 1998;106:85-92

9. Vasorelaxant and antioxidant activity of flavonols and flavones: structure-activity relationships.
OL Woodman, WF Meeker, and M Boujaoude
J Cardiovasc Pharmacol, Sep 2005; 46(3): 302-9.

10. Die Bedeutung der Passionsblume in der Heilkunde.
Lutomski J et al.
Pharmazie in unserer Zeit 1981;10:45-49.

11. The Honest Herbal: A Sensible Guide to the Use of Herbs and Related Remedies.
Tyler VE et al.
Pharmaceutical Products Press, New York, 1993.

12. Aphrodisiac activity of methanol extract of leaves of Passiflora incarnata Linn in mice.
K Dhawan, et al.
Phytother Res, Apr 2003; 17(4): 401-3.

13. Preoperative Oral Passiflora Incarnata Reduces Anxiety in Ambulatory Surgery Patients: A Double-Blind, Placebo-Controlled Study
Ali Movafegh, et al.
Anesth. Analg., Jun 2008; 106: 1728 - 1732.

14. Essential oils are novel human skin penetration enhancers.
Williams A, et al.
Int J Pharmaceuticals 57:R7-R9, 1989

15. Allyl-containing sulfides in garlic increase uncoupling protein content in brown adipose tissue, and noradrenaline and adrenaline secretion in rats.
Oi, Y. et al
J. Nutr. 129: 336-342. (1999)

16. Garlic Supplementation Increases Testicular Testosterone and Decreases Plasma Corticosterone in Rats Fed a High Protein Diet
Yuriko Oi, et al.
J. Nutr., Aug 2001; 131: 2150 - 2156.

17. Corticosterone Can Act at the Posterior Paraventricular Thalamus to Inhibit Hypothalamic-Pituitary-Adrenal Activity in Animals that Habituate to Repeated Stress
Azra Jaferi et al.
Endocrinology, Oct 2006; 147: 4917 - 4930

18. Study of the effect of sclareol glycol diterpene on the release of adenohypophysial hormones prolactin, somatotropin and adenocorticotrophic hormone
Georgieva et al.
Eksp Med Morfol. 1989;28(3):7-14. Bulgarian.

19. Study of the effect of sclareol glycol diterpene on the 3',5'-AMP level
Georgieva et al.
Eksp Med Morfol. 1989;28(3):1-7. Bulgarian.

20. Understanding True Aromatherapy: Understanding Essential Oils
Eileen D, et al.
Home Health Care Management Practice, Oct 2004; 16: 474 - 479.

21. Neuroactive flavonoids interacting with GABAA receptor complex.
F Wang, M Shing, Y Huen, SY Tsang, and H Xue
Curr Drug Targets CNS Neurol Disord, Oct 2005; 4(5): 575-85.

22. Prevention of chronic alcohol and nicotine-induced azospermia, sterility and decreased libido, by a novel tri-substituted benzoflavone moiety from Passiflora incarnata Linneaus in healthy male rats.
K Dhawan and et al.
Life Sci, Nov 2002; 71(26): 3059-69.

23. Passiflora: a review update.
Dhawan K, Dhawan S, Sharma A.
J Ethnopharmacol. 2004 Sep;94(1):1-23. Review.

24. A gamma-aminobutyric acidB agonist reverses the negative feedback effect of testosterone on gonadotropin-releasing hormone and luteinizing hormone secretion in the male sheep.
Endocrinology. 2000 Nov;141(11):3940-5.

25. Drug/substance reversal effects of a novel tri-substituted benzoflavone moiety (BZF) isolated from Passiflora incarnata Linn. ? a brief perspective.
Dhawan, et al.
Addiction Biology 379-386

26. Anticonvulsant effects of aerial parts of Passiflora incarnata extract in mice: involvement of benzodiazepine and opioid receptors.
Nassiri-Asl M, Shariati-Rad S, Zamansoltani F.
BMC Complement Altern Med. 2007 Aug 8;7:26.

27. Effects of Dialyzing γ-Aminobutyric Acid Receptor Antagonists into the Medial Preoptic and Arcuate Ventromedial Region on Lutienizing Hormone Release in Male Sheep.
Suzie A, et al.
Biology of Reproduction 58, 1038-1046 (1998)

28. Antiandrogen Microimplants into the Rostal Medial Preoptic Are Decrease γ-Aminobutyric Acidergic Neuronal Activity and Increase Luteinizing Hormone Secretion in the Intact Male Rat.
David R et al.
Endocrinology, Vol. 137 No. 10 (1996)

29. Non-classical estrogen modulation of presynaptic GABA terminals modulates calcium dynamics in gonadotropin-releasing hormone (GnRH) neurons.
Nicola Romano, et al.
Endocrinology, 10.1210/en.2008-0424 (2008)

30. Restoration of the Luteinizing Hormone Surge in Middle-Aged Female Rats by Altering the Balance of GABA and Glutamate Transmission in the Medial Preoptic Area
Genevieve S, et al.
Biol Reprod, Jul 2008; 10.1095/biolreprod.108.069831.

[Bam24]

Good info ! Will sit down n read later.. Pp was before me.. Kinda.. I was just out of the game during their reign :\

[Strong_Guy]

Was the recommendation to follow the 5 days on 2 off protocol with SA topical? Seems to me they moved away from that towards the end when the gel carrier came out and before it was discontinued.