Modular Series βAIBA

[totalflexblog]

Antaeus Labs Modular Series βAIBA is a dietary supplement containing β-aminoisobutyric acid.

Beta_aminoisobutyric_acid.jpg
Beta-aminoisobutyric acid, or BAIBA for short.

When you exercise, benefits of that exercise are seen in many different organs of the body, not just the muscles that were exercised. These metabolic benefits are the result of "messenger" molecules that are released into the blood stream and travel to other tissues where the benefits of exercise are realised. One such messenger molecule, or "myokine", is understood to be the amino acid beta-aminoisobutyric acid.
BAIBA is an amino acid that your body produces in response to exercise. After being released into the blood stream, it starts a thermogenic program in fat tissue, raising energy expenditure and reducing weight gain when tested in mice. When mouse or human white fat cells are exposed to BAIBA, some of them become fat-burning "beige" fat cells. Beige (or BRITE) fat cells contain the protein UCP-1 - also known as "thermogenin" because it burns triglycerides to produce heat.

- BAIBA is produced naturally by the human body – it’s formed from the catabolism of thymine [1][2] and is also product of exercise-induced PGC1a-mediated amino acid breakdown. [3]
- BAIBA increases the utilization of free fatty acids and decreases fat mass in mice. [4]
- BAIBA stimulates the differentiation of white fat cells into thermogenic beige/brite fat cells in both in vivo animal experiments and in vitro human stem cell studies. [5][6]

Antaeus Labs Modular Series βAIBA contains just the amino acid BAIBA, in powder form for easy dosing. It's tasteless and odorless, and mixes well with a soft drink or protein shake. It is suitable for both men and women.

βAIBA is suited for use by:
- those trying to lose weight, in combination with a healthy diet and exercise regime
- those trying to reap the maximal metabolic benefits from their exercise regime
- those who may be temporarily unable to exercise through injury or illness

βAIBA stacks well with: Antaeus Labs LipoMorph

1. β-Aminoisobutyric Acid, a New Probe for the Metabolism of DNA and RNA in Normal and Tumorous Tissue. Cancer Res 34, 1381–1384.
2. The excretion of beta-aminoisobutyric acid following thymine and dihydrothymine administration to man. Aust J Exp Biol Med Sci 39, 423–427.
3. PGC-1α-Mediated Branched-Chain Amino Acid Metabolism in the Skeletal Muscle. PLoS ONE 9, e91006.
4. Effects of zidovudine, stavudine and beta-aminoisobutyric acid on lipid homeostasis in mice: possible role in human fat wasting. Antivir. Ther. (Lond.) 9, 801–810.
5. β-Aminoisobutyric Acid Induces Browning of White Fat and Hepatic β-Oxidation and Is Inversely Correlated with Cardiometabolic Risk Factors. Cell Metabolism 19, 96–108.
6. Come on BAIBA Light My Fire. Cell Metabolism 19, 1–2.

These statements have not been evaluated by the Food and Drug Administration.
This product is not intended to diagnose, treat, cure or prevent any disease.

[totalflexblog]

βAIBA is available to buy now - and in the future could be as ubiquitous as beta-alanine, another amino acid that is very similar to BAIBA in both structure and origin (though with different effects).

[Hank!]

Here is the link to purchase
Antaeus Labs

[weekend]

according to the main study, they used 100-170 mg/mg per day... so thats 1/3 of a tub per day?

- - - Updated - - -

hopefully it's actually a 300g tub

[BBG]

Was that dose on rats? Rats have to megadose due to metabolism.... Doesn't convert mg/kg of weight to humans haha

[weekend]

yeah it was on rats. lol

[Hank!]

Found this
http://http://www.sciencedirect.com/...5041311300497X

To examine whether BAIBA could dose-dependently induce the expression of brown adipocyte-specific genes in WAT in vivo, mice were treated with 100 mg/kg/day or 170 mg/kg/day of BAIBA in drinking water for 14 days based on preliminary dose escalation studies.

Top dose was 170mg/kg in the rats

Ergo log says this the math to convert from rat to people
(170mg x 3)/37 = 13.78mg per km for Humans
for me at 245lbs the upper end of the dosing is 1.5gms a day. I would do 1gm a day so a tub is 30 days.

[BBG]

I have 2 tubs on the way and will start dosing at 1.5grams daily. About 200lbs right now.

[Bam24]

I have 2 tubs on the way and will start dosing at 1.5grams daily. About 200lbs right now.

What's the half life on this stuff. I'll prob do 1g per day so it lasts the full 30 days just hv to decided on 1. Or split dose


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[BBG]

Well I received 4 tubs instead of 2 so... still starting at 1.5grams but gonna dose higher.