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  1. #11
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    @swill

    Did you stack with anything such as an AI?

  2. #12
    Established Member Feedback Score 0 Swill's Avatar
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    Quote Originally Posted by Thanksgiving View Post
    @swill

    Did you stack with anything such as an AI?
    Yes, He tried both Anastrozole and Exemestane at varying doses right up to the full daily dose used for breast cancer treatment, none made me feel any better. It also didn't lower my E blood reading AT ALL, although I have read since that blood labs for E are meaningless whilst you are on clomid due to the effect the drug has on a mechanism in the brain - can't remember the exact science...someone here may know it a lot better than me.
    WORK! CONSUME! DIE!

  3. #13
    Established Member Feedback Score 0 entropy's Avatar
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    Quote Originally Posted by Swill View Post
    Yes, He tried both Anastrozole and Exemestane at varying doses right up to the full daily dose used for breast cancer treatment, none made me feel any better. It also didn't lower my E blood reading AT ALL, although I have read since that blood labs for E are meaningless whilst you are on clomid due to the effect the drug has on a mechanism in the brain - can't remember the exact science...someone here may know it a lot better than me.
    ... The supposed "reputable" endo was using bloods to judge your estrogen on a serm? AFAIK your estrogen will be higher on a serm as it just blocks the receptors. The raise it in T only happens cause you need the T to produce more estrogen. Its weird that AIs caused no change in bloods though..
    Cervix stabbing ftw.

  4. #14
    Established Member Feedback Score 0 Swill's Avatar
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    Quote Originally Posted by entropy View Post
    ... The supposed "reputable" endo was using bloods to judge your estrogen on a serm? AFAIK your estrogen will be higher on a serm as it just blocks the receptors. The raise it in T only happens cause you need the T to produce more estrogen. Its weird that AIs caused no change in bloods though..
    That's it I think Entropy, thanks. Dr Khera explained it to me along the lines of 'it works by making your brain think there is pretty much no estrogen, and as such you can get low estrogen side effects despite there being an abundance.'

    The 'supposed reputable' endo is Dr Crisler (All Things Male, based out of Lansing Michigan) and is an absolute fraudster with a God complex. He has been purporting to having the answer for a lot of people to finasteride related issues since around 2009, and as a result the early days of being hit with this thing I flew over to him and went under his care. He couldn't help and I dumped him when I realised I was being used as a guinea pig somewhat and paying for the privilege after 6 months. He is an anti-ageing doc and has his own forum and is apparently well respected particularly by many in the bodybuilding movement. He also didn't send me a product I ordered off him for 8 months and stopped replying to emails regarding it, and in the end I had to claim the money back through my credit card company. Total fraudster. He claimed to be cutting edge but the guy had never ever used exemestane before me... hindsight is a great thing.

    But yeah, it was weird that an AI didn't touch the E level in my bloods, and this was also supported by several 24 hour urine panels each time. One month he increased my AI dose substantially and we tested a month later and my E had actually risen. The stuff I was using was legit UK scripted stuff through my GP too so no doubts about that. The doc said he had never seen anyone aromatise like me ever. But it seems I just didn't get on well with Clomid, I can boost my T levels with herbs and successfully hammer down my Estrogen with an AI (exemestane), as I have found out with bloods this month.
    Last edited by Swill; 07-16-2015 at 02:17 PM.
    WORK! CONSUME! DIE!

  5. #15
    A 1k Club Member Feedback Score 0 Jelisej's Avatar
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    Quote Originally Posted by Thanksgiving View Post
    Clomid increases test.
    One would think with the increased test, it would have an anabolic effect so long as one controls estrogen.
    Why doesn't this seem to be the case?
    Firstly, increase of testosterone on clomiphene is not really that significant,
    Secondly, for anabolism you need other raise some other hormone levels (for example IGF) and sometimes IGF levels while on clomiphene drops (dont know exact details here)

    Also E2 has impact on IGF levels and some other levels, and it needs to be in optimum levels as well- if its too low then its hard to get any anabolism and if its o high than body starts packing up fat rather tham muscles, and its hard to get correct E2 blood results while on SERMS also most of AI's reduce IGF levels on its own (aromasin does not)
    Also low estrogens also weakens bones (every time AI's are used vitamin D should be added/dosages increase)

    And SERMS also have negative impact on libido which is big deterent for most of people

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