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  1. #12
    Established Member Feedback Score 0 TubZy's Avatar
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    There isn't much info on 5b-DHT but I also found this. It seems to be the easiest to understand.

    5b or not 5b? - Total Flex BlogTotal Flex Blog

    "The conformational change involved in 5b-reduction makes the steroid anything but flat, and an extremely poor fit for the receptor. By way of an example, 5a-DHT has 173 times stronger binding affinity than 5b-DHT. [3] 5b-reduced steroids are effectively inactive."

    "The upshot being, if any superdrol clone was using a 5b-isomer of the methasteron molecule, it wouldn’t be “weaker”, it quite simply wouldn’t work."

    "A few years ago people began to notice that certain brands of superdrol clones list the active ingredient as 2a,17a-dimethyl-etiocholan-3-one-17b-ol, believing this to indicate that the steroid inside is 5-b reduced version, or a “b-isomer” of superdrol. Many even go so far as to use this as an explanation for cycles with these drugs that do not meet the expectations of the user, citing the “weaker b-isomer” as the excuse for the poor results."
    Last edited by TubZy; 03-20-2017 at 04:47 PM.

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