thoughts on progesterone / pregnenolone

[JoeP26]

Is applying andro a bandaid fix or will it change the way receptors function in the longterm?

Any kind of exogenous hormone use will change epigenetic expression. Androsterone should change the expression in the long run for the better. But not EpiAndrosterone.

- - - Updated - - -

Thanks for the well thought out response man. I appreciate it

Sure thing!

- - - Updated - - -

Could you in a way counteract the epi with big doses of theanine to partially activate the glutamate instead?

No

- - - Updated - - -

I oddly respond better to the blend of Epi and Andro (Ultra Hard) rather than just pure Andro.

I somewhat enjoy the stimulating effect Epi has, whereas I just don’t feel pure Andro as much. I think others have responded better to the blend as well. Maybe there’s some genetic variance here?

Depends on how upregulated the individual's GABAA receptors are.

[Karlucchi]

Any kind of exogenous hormone use will change epigenetic expression. Androsterone should change the expression in the long run for the better. But not EpiAndrosterone.

- - - Updated - - -

Question about this statement. Using UltraHard (Epi and Andro) would still downregulate AR receptors correct? Just not help with the GABAA receptors as much as just Androsterone alone would?

[JoeP26]

- - - Updated - - -

Question about this statement. Using UltraHard (Epi and Andro) would still downregulate AR receptors correct? Just not help with the GABAA receptors as much as just Androsterone alone would?

It will but it will also upregulate GABAA receptors and this may make problems worse for some who are neurosteroid deficient in the brain and already have severely upregulated GABAA receptors. Androsterone solo products would prevent that and actually help downregulate GABAA, which you'd typically want in PFS.

[Jado]

It will but it will also upregulate GABAA receptors and this may make problems worse for some who are neurosteroid deficient in the brain and already have severely upregulated GABAA receptors. Androsterone solo products would prevent that and actually help downregulate GABAA, which you'd typically want in PFS.

Great info, man

[Mojo]

Now I just need someone to tell me how to get my hands on some andro in the EU

[Mojo]

Looking for some andro products available in the EU I came across this:

https://www.predatornutrition.com/pr...o+Testosterone)

Blend:
Androsterone (150mg)
1 androstene-3b-ol,17-one (50mg)
4 androstene-3b-ol,17-one (50mg)
Arimistane (50mg)

I'm doubtful about the Arimistane (which is an aromatase inhibitor)

Thoughts?

[Benq123]

for me personally it was huge. I got the bulk of my personality back from preg. still missing that 'killer instinct' at times though but it's there at others.

Did you take oral or topical pregnenolone and what dose? Thanks