I don't want to provoke anything but how much of this is in our heads? If I were to do the program as outlined and came home to a prison cell with no tv, internet, work stress etc. would I heal faster? If PFS is to do with some part of the brain not relaxing wouldn't living in a stress free environment be the most conducive to recovery? How much is day to day stress hampering things.. I think the working theory is that once the enzymes recover then the brain calms down but English was almost alluding this thing to being purely mental, like some type of neural pattern that's causing the stress. ANRS and the gupta method, which are programs aimed at cfs, are basically saying that those chronic stress conditions are due to neural patterns and thoughts rather than some physiological issue. Can one recover without changing their thoughts to positive ones? If the enzymes are restored wouldn't we feel this happen even in a negative state of mind therefore boosting our mood and optimism?