ITPP?

[weakling]

sorry if this is the wrong thread for this question. Mod feel free to move, delete etc if needed.

Ok I've googled and I can not find many reviews. What is it, how does it work, how to dose, etc? I would like to know before giving it to my rat. Thanks

[Cobalt]

I don't think you'll find much info on it, Skyward is the only company selling it right now.

I'm looking into it myself, I'm trying to design a dosing protocol:

A starting dose would be 0.55 mg/kg of weight, then increased to 0.8 mg/kg depending on reactions to the starting dose.
A maximum dose of 1.1 mg/kg may be tested, depending on prior response.

My biggest desire is to find the half-life of the chemical, and how long it takes the body to absorb it.
I can't imagine it taking over an hour to absorb, but the HL could be anywhere on the map.

I think I'll have my rats take it an hour prior to exercise and see how they respond.

EDIT:
Just uncovered this, it is worth the read:
Enhanced exercise capacity in mice with severe heart failure treated with an allosteric effector of hemoglobin, myo-inositol trispyrophosphate

It seems ITPP has a half-life of around 5 days.

[weakling]

Nice find. Very interesting

[Scope75]

I was sent these when I asked BBG about this.
Study 1: Enhanced exercise capacity in mice with severe heart failure treated with an allosteric effector of hemoglobin, myo-inositol trispyrophosphate

Study 2: (interesting one on ITPP and reducing cancer growth) Increasing the oxygen load by treatment with myo-in... [Oncogene. 2012] - PubMed - NCBI

Study 3: Enhanced exercise capacity in mice ... [Proc Natl Acad Sci U S A. 2009] - PubMed - NCBI

[SkywardResearch]

You really won't find any reviews of research on this compound. We are striving to bring out a lot of new research chemicals over the next few weeks (yes, weeks not months!!). Raloxifene will be added soon, an oral Growth Hormone secretagogue... some other very nice stuff as well.

ITPP is very interesting. It helps the heart and muscles grab more oxygen from the blood. The research implications are pretty cool, I think.

Scope, you're getting some in your order when the Ostarine and ITPP come in. Really sorry about the delay, guys.

[nate3993]

You really won't find any reviews of research on this compound. We are striving to bring out a lot of new research chemicals over the next few weeks (yes, weeks not months!!). Raloxifene will be added soon, an oral Growth Hormone secretagogue... some other very nice stuff as well.

ITPP is very interesting. It helps the heart and muscles grab more oxygen from the blood. The research implications are pretty cool, I think.

Scope, you're getting some in your order when the Ostarine and ITPP come in. Really sorry about the delay, guys.

go on..

[Scope75]

You really won't find any reviews of research on this compound. We are striving to bring out a lot of new research chemicals over the next few weeks (yes, weeks not months!!). Raloxifene will be added soon, an oral Growth Hormone secretagogue... some other very nice stuff as well.

ITPP is very interesting. It helps the heart and muscles grab more oxygen from the blood. The research implications are pretty cool, I think.

Scope, you're getting some in your order when the Ostarine and ITPP come in. Really sorry about the delay, guys.

Sounds like some great things are coming and I can't wait for my order.

Oh and as soon as I receive my order I'll start up a log for the ITPP!!
Then I'll log the Osterine.
2013 is starting off great.

[Cobalt]

Damn my christmas spending, I need more monies to get my research going again!