Phosphatidylserine in Res100 reduces cortisol and increases Testosterone
A reduced level of cortisol will offer the following benefits:
• Improve the testosterone to cortisol ratio
• Increase resistance to stress & fatigue
• Increase exercise capacity
• Speed recovery & reduce muscle soreness
• Enhanced sense of well-being
What are some signs that my cortisol is too high?
• Excess fat distribution around the face and/or abdominal area
• Low Libido
• Low Testosterone
• Low GH (Growth Hormone)
• Decreased insulin sensitivity
• Suppressed immune system
• Mental depression
• Easily fatigued or exhausted
• Prolonged recovery from exercise
Full Study Extract here: JISSN | Full text | The effects of phosphatidylserine on endocrine response to moderate intensity exercise
Figure 1 shows the effects of S-PS or placebo supplementation on cortisol, testosterone, lactate and growth hormone response to exercise-induced stress at -30, 0, 15, 20, 30, 40, 60, and 80 minutes after exercise. Mean peak concentrations are shown in table 2.
Cortisol, testosterone, lactate and growth hormone response to exercise after 10 days of oral treatment with 600 mg S-PS or placebo (pre-exercise phase -30 to 0 minutes, exercise phase: 0 to 15 minutes, recovery phase 16 to 80 minutes).
Starks et al. Journal of the International Society of Sports Nutrition 2008 5:11 doi:10.1186/1550-2783-5-11
S-PS supplementation resulted in significant lower plasma cortisol levels at the beginning of the exercise (p = 0.002) when compared to placebo. Differences for testosterone (p = 0.20) and growth hormone levels (p = 0.30) were not significant.
S-PS supplementation reduced plasma cortisol concentrations by 39 ± 1% when compared with placebo (treatment effect: F = 6.7, p = 0.03; treatment × time interaction effect: F = 8.3, p = 0.05). Plasma testosterone concentrations increased with S-PS (51 ± 6%) when compared with placebo; however, differences between groups failed to reach statistical significance for the effect of treatment (F = 2.79, p = 0.13) and treatment × time interaction effect (F = 0.35, p = 0.87). Exercise resulted in an increase in lactate levels in both groups, however, the increase failed to reach statistical significance (time effect: F = 5.41, p = 0.06). Supplementation did not result in significant differences in lactate response between the S-PS and placebo groups (treatment effect: F = 0.47, p = 0.51; treatment × time effect: F = 1.62, p = 0.34). Similarly, supplementation did not influence plasma growth hormone concentrations (treatment effect: F = 2.49, p = 0.15) or the pattern of response (treatment × time interaction effect: F = 0.75, p = 0.66).
S-PS supplementation resulted in a favorable physiological state when compared to the placebo group. Area under the curve analysis (figure 2) showed significant differences between S-PS and placebo for cortisol (35 ± 0% reduction, p < 0.01), testosterone (37 ± 5% increase, p = 0.02), and testosterone to cortisol ratio (184 ± 5% increase, p = 0.02, figure 2).
S-PS significantly decreased cortisol (35 ± 0%, p < 0.01) and increased testosterone (37 ± 5%, p = 0.02) AUC levels and testosterone to cortisol ratio (184 ± 5%, p = 0.02) in comparison to placebo.
Starks et al. Journal of the International Society of Sports Nutrition 2008 5:11 doi:10.1186/1550-2783-5-11