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  1. #21
    Super Moderator Feedback Score 0 burlyman30's Avatar
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    Re: The Most Independently reviewed and blood tested Testosterone Booster

    Quote Originally Posted by O.N. View Post
    Here is the link:
    Linus Pauling Institute at Oregon State University



    Meaning when estrogen is present it lowers estrogen and when there is an absence it can act as estrogen.
    Thank you, O.N.
    All advice given is for entertainment value only. And it's free. Take it for what it's worth.

  2. #22
    Sponsor Feedback Score 0 O.N.'s Avatar
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    Quote Originally Posted by burlyman30 View Post
    Supporting links, please.
    D-Aspartic Acid and the secret to Italian Loving

    The brain consists of D-Aspartate being converted into a very prominent signaling metabolite called NMDA (N-methyl-D-Aspartate). This influx of NMDA in the anterior pituitary and hypothalamus causes an acute secretion of Growth Hormone Releasing Hormone (GHRH), Prolactin releasing factors (PRFs), and Gonadotropin Releasing Hormone (GnRH). These hormones then induce production and secretion of Growth Hormone (GH), Prolactin, and both Follicle Stimulating hormone (FSH) and Luteinizing hormone (LH). (Another nice source)

    It’s basically an anabolic cascade.

    It also suppresses dopamine release (temporarily), so it’s not all perfect (and with the secretion of Prolactin, not too good of a combo for a prolonged period of time).

    Finally, it seems to induce release of both Melatonin-stimulating factor and GABA (a relaxing neurotransmitter) in the hypothalamus, suggesting that D-Aspartic acid would be better taken in the PM.

    also more detailed info here all are from human trials: D-Aspartic Acid - In-Depth Scientific Supplement Information | Examine.com just search for key words in the text like prolactin melatonin etc
    Res100 the most powerful Testosterone Booster www.WickedSupplements.com
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  3. #23
    Super Moderator Feedback Score 0 burlyman30's Avatar
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    Re: The Most Independently reviewed and blood tested Testosterone Booster

    Quote Originally Posted by O.N. View Post
    D-Aspartic Acid and the secret to Italian Loving

    The brain consists of D-Aspartate being converted into a very prominent signaling metabolite called NMDA (N-methyl-D-Aspartate). This influx of NMDA in the anterior pituitary and hypothalamus causes an acute secretion of Growth Hormone Releasing Hormone (GHRH), Prolactin releasing factors (PRFs), and Gonadotropin Releasing Hormone (GnRH). These hormones then induce production and secretion of Growth Hormone (GH), Prolactin, and both Follicle Stimulating hormone (FSH) and Luteinizing hormone (LH). (Another nice source)

    It’s basically an anabolic cascade.

    It also suppresses dopamine release (temporarily), so it’s not all perfect (and with the secretion of Prolactin, not too good of a combo for a prolonged period of time).

    Finally, it seems to induce release of both Melatonin-stimulating factor and GABA (a relaxing neurotransmitter) in the hypothalamus, suggesting that D-Aspartic acid would be better taken in the PM.

    also more detailed info here all are from human trials: D-Aspartic Acid - In-Depth Scientific Supplement Information | Examine.com just search for key words in the text like prolactin melatonin etc
    "Shown to upregulate aromatase enzyme in boar and lizard testes" is all it says. And this would happen if testosterone levels rose.
    All advice given is for entertainment value only. And it's free. Take it for what it's worth.

  4. #24
    Sponsor Feedback Score 0 O.N.'s Avatar
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    Quote Originally Posted by burlyman30 View Post
    "Shown to upregulate aromatase enzyme in boar and lizard testes" is all it says. And this would happen if testosterone levels rose.
    Yeah agreed if test goes up so will estrogen conversion however the words up regulate aromatase enzyme do not sound great. The tests would need to be of greater detail showing the testosterone:estrogen ratio (T:E) to see if supplementing with DAA alone alters this ratio or if simply put both raise equally.

    I do not think that has been studied as of yet.
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  5. #25
    Sponsor Feedback Score 0 O.N.'s Avatar
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    Involvement of D-Asp in P450 aromatase activity ... [Amino Acids. 2007] - PubMed - NCBI

    Endocrine roles of D-aspartic acid in the testi... [J Endocrinol. 2005] - PubMed - NCBI

    http://www.reproduction-online.org/c...5/803.full.pdf
    from the above PDF:

    The physiological mechanism underlying the inverse and direct relationships between D-Asp and, testosterone and oestradiol, respectively, were evident from the results of the experiments in vitro. The results showed that when D-Asp is added to an incubation medium containing testosterone and either homogenate or acetone powder extracts of ovarian follicles, a significant increase in aromatase activity occurs, which converts testosterone to oestradiol. Aromatase was characterized using linear Michaelis–Menten plots. Furthermore, the aromatase activity was four times greater in the presence of D-Asp than in its absence; however, the nearly equivalent values of the two K m values (both approximately 25 nmol l –1 ) indicate that aromatase has the
    same catalytic properties in both cases
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  6. #26
    Established Member Feedback Score 0 markam's Avatar
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    Quote Originally Posted by szary View Post
    I think AI makes you wise user you can fight prolactine continuously or just one time a day or once every second day aromatization of testosterone to estrogen but this doesn't solve the problem of to low estrogen in the bloodstream specifically "good" estrone" involved in joins wellness and some anabolism of muscle tissue. With stopping the aromatisation by ingesting AI (specifically permament AI type steroid based not like in RES 100 WHERE AI IS FLAVONE BASED NON PERMAMENT)YOU CUT NOT ONLY the bad 17 estradiol type of estrogene you also hurt yourself by cutting "good estrone" estrogen . Every action has a reaction, and there are always unintended consequences.

    I just wanted to add that manufactures and distributors of AIs bsed on flavons not permamently inhibiting aromatase rarery declare benefits of such inhibitors compare to AI based on steroids (ATD, 6-BROMO arimistane etc.) which could have severe side effects
    Thanks, excellent post. Personally I wouldn't feel comfortable using only resveratrol with DAA especially if the DAA was doubled dosed. I was considering maybe 50mgs 6-Bromo, but perhaps you have a better suggestion, and maybe a OTC alternative? I've found Triazole to be effective in some circumstances, but whether it would be strong enough in this instance, I don't know.

  7. #27
    Sponsor Feedback Score 0 O.N.'s Avatar
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    Be sure to check out our new website: RES100 Wicked Supplements
    Last edited by O.N.; 01-02-2014 at 09:42 PM.
    Res100 the most powerful Testosterone Booster www.WickedSupplements.com
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  8. #28
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    Lots of big things happening this year.....including a clinical trial, stay tuned more info to come in the next few weeks.
    Res100 the most powerful Testosterone Booster www.WickedSupplements.com
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  9. #29
    Sponsor Feedback Score 0 O.N.'s Avatar
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    We had a meeting today with the University of NSW in regards to conducting our clinical trial, it looks like it will take a little time to get it underway however all things today were positive and it looks like conducting the trial will not be an issue.
    Res100 the most powerful Testosterone Booster www.WickedSupplements.com
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  10. #30
    Sponsor Feedback Score 0 O.N.'s Avatar
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    Res100 the most powerful Testosterone Booster www.WickedSupplements.com
    We Ship World Wide! Save 10% with members only discount: SS10 Order Online: www.OnlineNutrition.com.au

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