Im reading about the clomid and seeing that a lot of people are using nolvadex. Any thoughts on that?
Im reading about the clomid and seeing that a lot of people are using nolvadex. Any thoughts on that?
Citing the Sinners post on serms from "No Excuses & No ***** ***: A Stupid People's Guide to PCT"
The Different SERM’s:
Tamoxifen (Nolvadex):
Reputation: Most popular SERM for PCT
Pros: Cheap. Effective for gyno prevention.
Cons: Heptatoxicity. Studies have shown it to lower IGF levels (I don’t feel like citing, but it’s about 20% decrease…IMO no biggie).
Popular Dosage (for a 4-week cycle): 40/40/20/20
Note: Tamoxifen Citrate is less potent, and should be dosed at an extra 30%.
Clomiphene Citrate (clomid):
Reputation: Second most popular. Usually taken the first week or so to speed up Testosterone recovery with Tamoxifen being taken the whole therapy.
Pros: Better than Tamoxifen for HTPA regernation. Less heptatoxicity. Does not lower IGF.
Cons: Less effective against gyno. Can cause emotional issues. May Cause blurred vision. Hot Flashes.
Popular Dosage (for a 4-week cycle): 100-200mg/100mg/50mg/50mg
Toremifene:
Reputation: Very popular on this board
Pros: Much less toxic.
Con’s: $$$$$expensive$$$$$
Popular Dosages (for a 4-week cycle): 120-240mg/120mg/60mg/30mg
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they are smarter since clomid is due to containing an additional chlorine atom
A more reactive - the doses need to be higher and could fluctuate in effectiveness
B more toxic - it can cause some carcinogenic issues
C does not cross the blood-brain barrier as easily (or at all) like tamoxifen
D biding affinity to estrogen receptors are almost the same (in trials ) so no need to run 2 SERMS(in UK many run clomid and nolva)
E effectiveness in treatment of male hypogonadism is the same ( it consists of broscience on hearsay )
If you have access to nolva take it it's better
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i think toremifene is your best bet. no sides, while clomid did give me mild emotional sides and a slightly noticeable decrease in night vision acuity.
exemestane doesn't affect the lipid profile... might be a good addition since SOS500 has LMG (estrogenic) and SD (can cause rebound gyno)
but i don't have experience using exemestane in PCT except just recently but i ran out on like day 10...