
Originally Posted by
JoeP26
It's legit stuff. But you're only raising serum levels of DHP and Allo. Some makes it into the brain but not all of it because of the blood brain barrier. The brain itself has P450 enzymes that create its own sex steroid environment separate from the body and that's what gets shut off from 5 alpha reductase inhibitors. Progesterone itself in the brain also consistently gets shuts off, rendering the oral DHP mostly useless for the brain because the half life is so short and there's insufficient progesterone to make it naturally in the brain. However, it's still good for stimulating it in the blood serum because it can be low there too, unless your serum progesterone is also low. Give it a try and see what happens. Worst it does is nothing.