For those that buy into the one-hour rule

[Sperwer]

I'm also a fan of phosphatidyl serin (still have a stash of endo amp), but whether that is a panacea or even part of the treatment for any particular instance of chronically elevated cortisol would depend I think on the specific etiology of that instance. One of the things I learned from Sapolsky's book is that the causes can be varied, numerous and interactive with one another and produce a cascade of effects. Just trying to treat one symptom or modulate one pathway of elevated cortisol without an understanding of the whole syndrome in the case presented probably would not be optimally effective or effectual at all. As Rodja says, chronically elevated cortisol is likely a sign that a (major) lifestyle change is in order.