Originally Posted by
Zonz
Post Finasteride syndrome is, in my opinion, exposes some sort of weakness in the androgen receptor where they don’t function properly after being inhibited.
We live in a country (if you’re in the US) where there are literally endocrine disrupters in the air you breathe and the water you drink in the form of pollutants such as pesticides and neonicotinoids. Stack that with a drug that inhibits androgen receptors such as Minoxidil* along with weak androgen receptor genetics (high IQ/high immune system individuals, look into CAG repeats for an example of this correlation) and you get PFS.
*I debunked the two studies you posted but the site was down so it’s lost. In short, my studies are from 2014 and 2017 respectively while yours are from 1987 to 1999, to put time into perspective. The gains in knowledge we have on endocrine disrupters in that time frame is huge. The 2014 study directly addresses both of the studies you posted, the Syrian hamster one (which studies testosterone, not DHT or 5arII/ARs, in FEMALE rats) and the 1999 one which saw a very small increase in 5arII that could be considered negligible. The two studies I posted are very comprehensive, I’ve read the 2014 Korea one from top to bottom and it’s indisputable evidence that Minoxidil is indeed an anti androgen. It literally images the androgen receptor and how minoxidil inhibits it’s function on a micro cellular level. With my own personal experience with Minoxidil, I DO find it has an anti androgenic effect on me because my skin went pale and dry after applying and a heavy brain fog sets in almost instantly after applying.
I never took any other drug other than 5% Kirkland Minoxidil for 6 months, twice per day, although I did rub peppermint oil on my scalp once in an attempt to grow hair. My priorities were out of whack back then.
Again not trying to disrespect you but I have my suspicions you might be on Minoxidil or a similar drug, which is fine, we all have the desire to keep our hair. And maybe you have the genetics to handle the endocrine disruption. Who knows. But Min IS antiandrogen and can cause PFS since it’s applied systemically twice daily in large dosages.